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submitted 2 months ago by drmoose@lemmy.world to c/science@lemmy.world

French researchers have established the first direct causal link between mitochondrial dysfunction and memory loss in neurodegenerative diseases, demonstrating that restoring brain energy production can reverse cognitive symptoms within hours.

The study, published August 11 in Nature Neuroscience by scientists from Inserm and the University of Bordeaux, developed a precision tool called mitoDREADD-Gs that successfully restored memory function in multiple dementia mouse models by directly stimulating mitochondrial energy production.


"This work is the first to establish a cause-and-effect link between mitochondrial dysfunction and symptoms related to neurodegenerative diseases, suggesting that impaired mitochondrial activity could be at the origin of the onset of neuronal degeneration," said Marsicano.

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[-] FurryMemesAccount 39 points 2 months ago

I mean, this is obvious. As the cells have an energy problem, it had to be related to the powerhouse of the cell. I could have done this myself.

/s

Let me grab some more power

this post was submitted on 13 Aug 2025
234 points (100.0% liked)

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