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submitted 1 week ago by AddLemmus@lemmy.ml to c/adhd@lemmy.world

My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

Can it really be so much different? Both claim to have a 50 % instant-release part.

Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-removedpraeparaten.html

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[-] Siethron@lemmy.world 2 points 1 week ago

Adult on time release generic methylphenidate here. I notice it usually starts working about 45 minutes after ingestion. Instant release only really means as soon as it begins to be digested and everybody's body is different.

Also remember, don't mix it with caffeine or the effects will be greatly reduced.

this post was submitted on 21 Jul 2025
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