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submitted 2 weeks ago by AddLemmus@lemmy.ml to c/adhd@lemmy.world

My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

Can it really be so much different? Both claim to have a 50 % instant-release part.

Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-removedpraeparaten.html

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[-] spankmonkey@lemmy.world 3 points 2 weeks ago

I am on the extended release (ER) for methylphenidate on a high dose for like 20 years and for me it lets me focus while it is working.

Sustained release (SR) does not work nearly as well for me. Standard release wears off way too fast.

People have very different rates of success or side effects so yes, it really could be that different! It sounds like this isn't the right one for your kiddo.

this post was submitted on 21 Jul 2025
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