LONDON, Ky. (AP) — Storm systems sweeping across parts of the U.S. Midwest and South have left at least 23 people dead, many of them in Kentucky, where what appeared to be a devastating tornado crumbled buildings and flipped over a car on an interstate.

In Kentucky, some 14 people were killed by severe weather, and the death toll is likely to rise, according to Gov. Andy Beshear. Local authorities in Laurel County, in the state’s southeast, said nine people were killed after a tornado touched down.

Rescuers were searching for survivors all night and into the morning, the sheriff’s office said. An emergency shelter was set up at a local high school and donations of food and other necessities were arriving.

The National Weather Service hadn’t yet confirmed that a tornado struck, but meteorologist Philomon Geertson said it was likely. It ripped across the largely rural area and extended to the London Corbin Airport shortly before midnight.

The storm was the latest severe weather to cause deaths and widespread damage in Kentucky. Two months ago, at least 24 people died in a round of storms that swelled creeks and submerged roads. Hundreds of people were rescued, and most of the deaths were caused by vehicles getting stuck in high water.

A storm in late 2021 spawned tornadoes that killed 81 people and leveled portions of towns in western Kentucky. The following summer, historic floodwaters inundated parts of eastern Kentucky, leaving dozens more dead.

About 1,200 tornadoes strike the U.S. annually, and they have been reported in all 50 states over the years. Researchers found in 2018 that deadly tornadoes were happening less frequently in the traditional “Tornado Alley” of Oklahoma, Kansas and Texas and more frequently in parts of the more densely populated and tree-filled mid-South area.

The latest Kentucky storms were part of a weather system Friday that killed seven in Missouri and two in northern Virginia, authorities said. The system also spawned tornadoes in Wisconsin, brought a punishing heat wave to Texas and temporarily enveloped parts of Illinois — including Chicago — in a pall of dust on an otherwise sunny day.

The National Weather Service’s Storm Prediction Center said on its website Saturday that severe thunderstorms, large hail and “a couple of tornadoes” were expected across the southern Plains, with especially high risk in north Texas.