YunoHost is very nice to run on a VPS (or a box at home, or anything). It has good email hosting support, and I feel people without systems administration experience could get it running and host a couple of apps for a group without too much trouble.

TrueNAS Scale has awesome NAS capabilities. ZFS is the bomb. Plus, they are integrating Incus, which I'm a huge fan of. I think it hits a sweet spot for people with systems administration experience. Just install it and you get great NAS capabilities, the option of running a K8S instance, LXC/VM capabilities, and some "app catalog" (I test drove that briefly and it looked decent, but I think less hands-free than Yunohost.). My pet peeve (and I understand why they do this) is that you need separate drives for the OS and for data, so if you want redundancy you need 4 drives- which is likely fine for home use, but I'd like to run TrueNAS Scale on a Hetzner dedicated server, and that increases costs a lot.

If your primary desire is to run a few apps and you want to minimize your learning/effort, I'd check out YunoHost. If you want to do more, but also invest more time, TrueNAS Scale is awesome.