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Microsoft is killing OneNote for Windows 10
(www.neowin.net)
This is a most excellent place for technology news and articles.
I've been using Any.type for a bit over a year, and am very happy with it, but I don't believe it has hand writing support.
There is a free tier that includes 1gb synced storage (optional).
It's open source. Somewhat similar to Obsidian, but no plugin support that I'm aware of.