I didn't address that one because the commenter qualified it by saying you can't easily change them, which is kind of true. You can change the modifiers, but anything beyond that or changing keyboard layouts is a crapshoot in my experience.

It's considerably better than trying to remap anything on Windows, at least. But, it's also not completely free from hard-coded hotkeys and dumb restrictions. For example, Command + Tab can't be changed or disabled, and you need to use third-party programs like BetterTouchTool to hijack the sequence in order to replace it with some other action.

More recently, I read that the latest OS version disallows registering hotkeys with only Option or Option+Shift as the modifier, which is a very big step backward. Being able to insert unicode characters is cool, but it's peanuts compared to having 80 more options for hotkey sequences that aren't already used by the OS or application.