I love how the mathematician ends the interview by saying

[this] may help us uncover something beautiful, or maybe even useful.

It's great seeing how these people work with science for the sake of science itself, because it's beautiful, not because they suspect that they'll find something that immediately changes the world. It makes me think that they see themselves more as artists than as engineers, and I think that if you have a career in science it's a healthy approach to have. Most scientists never have an "Einstein-like" breakthrough, but contribute pieces to the puzzle that may lead to breakthroughs long after they're gone. Being satisfied with that is probably key to having peace of mind as a scientist.