If I'm into the story, yes. Feel like this kind of question doesn't understand that a lot of stories only have going for them resolving one or two questions. Once you know the answer the rest of the story is so average it's hard to care to finish. For example I read a lot of otome isekai (tl;dr romance novels where the heroine was sucked into a novel/game). Once you know the twist it's just a subpar story.

That said if a story is kind of shitty and I'm considering dropping it, but I read a spoiler the twist is actually really good and puts the crappy parts in an interesting context I'll keep reading. So case by case, reader by reader basis. I have stories I only finished because I read a spoiler, but I have just as many I never finished because I read a spoiler.