I think that interoperation with big walled gardens is part of the reason why #activitypub exists. Furthermore, there are no technical measures to completely shut off #Threads, and the social measures are unlikely to work.
I know the risks, I'm old enough to remember #Microsoft embracing and extinguishing browsers and open documents, #Goggle defederating from #XMPP and #Facebook predatory tactics.
On the other hand, I think that federation with the big players is unstoppable. The protocol is open and there is no way to get every last instance to defederate. If people want to see the big players' content they'll move to an instance that federates with them. And defederating from those that connect to threads sounds like a Zealot's suicide pact.
I think that the best way to ensure that #Meta plays fair is to create a fediverse that is as diverse, open and vibrant as possible, with plenty of open services (Lemmy, mastodon, misskey...) and commercial ones (Flipboard, tumblr...) so that threads users will feel compelled to interact and miss us if Meta stops federating or shadowbans external content.